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Abnormalities in Ipsilateral Silent Period in the High-Risk for Alcohol Dependence: A TMS Study
Kesavan Muralidharan, Ganesan Venkatasubramanian, Pramod K Pal and Vivek Benegal
Central Nervous System (CNS) disinhibition has been reported to underlie the vulnerability to alcohol dependence (AD) in individuals with a high-family loading of AD [1]. Maturational lag and defective myelination of particular brain regions, including the corpus callosum(CC), have been reported in these individuals [2]. Morphometric studies reported significantly smaller total CC, genu and isthmus areas in these individuals after controlling for age and intracranial area [3].
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