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Benign Paroxysmal Positional Vertigo from the Perspective of Vitamin D

Zhiling Yang, Binjuan Ma, Jian He, Min Xie

Vitamin D (VIT D) is involved in maintaining Ca2+ homeostasis in the endolymph playing a primary role in synthesis of otoconia made up of calcium carbonate. VIT D deficiency which has been associated with Benign Paroxysmal Positional Vertigo (BPPV), results in an abnormal morphological structure of otoconia and subsequent otolith dysfunction. Although the association between VIT D deficiency and recurrence of BPPV was indefinite, many studies indicated that VIT D supplementation was beneficial for BPPV.