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Biofilm Formation on Medical Implants

Michal Besterci

On biomedical implants, biofilm development occurs. In contemporary medicine, microbial infections in biomedical implants are a major hazard. Biofilm infection is still a primary cause of biomaterial implant failure. All medical equipment are susceptible to microbial pathogen colonisation. Biofilm is a sessile microbial community characterised by cells that are permanently connected to a substratum or interface to each other and immersed in a matrix of extracellular polymeric substances that they have generated. Biofilms are a complex microbial community that adheres to the exopolysaccharide matrix on the surface of medical devices.