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Craniopharyngioma square measure benign tumors of embryonic origin placed within the seller region.Patients have each neurologic and endocrinological symptom. Symptoms is also delicate within the early clinical course, that results in delayed designation. This study evaluated the clinical and endocrinological manifestations of childhood-onset craniopharyngioma. We retrospectively reviewed medical records of forty five kids diagnosed as having craniopharyngioma between we tend to collected information on clinical symptoms and signs, height,weight, organic chemistry and endocrine information, images, operation records, and pathology reports. A threegraded system was applied to outline the degree of neural structure injury (HD). We tend to analysed clinical and endocrinological manifestations among patients with and while not fatness, with short and traditional stature, and with differing degrees of HD.