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Collision Metastasis of Chronic Lymphocytic Leukemia and Glioblastoma: A Case Report
Sandra C Yan, Nelli S Lakis, Edward G Stopa and Curtis E Doberstein
Collision tumors or metastasis from an extracranial tumor to a primary brain neoplasm are rare but do occur. The majority involve metastases to meningiomas. This case presents the second documented collision of a systemic chronic lymphocytic leukemia (CLL) to a glioblastoma multiforme (GBM). Lymphomas tend to coalesce in perivascular locations, and the characteristic vascularity of glioblastomas may present a very inviting milieu for lymphoma cells.
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