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Santosh J Gutte*
Helminthiasis is the most common cause of the intestinal infestation. Anthelmintic from natural sources may play a key role in the treatment of parasitic infestation. Aqueous extracts from the seed of Centratherum Anthelmintic (L).were investigated for their anthelmintic activity against Earthworm (Eisneia Fetida). Mebendazole is used as the Standard drug. Extract was studied in the bioassay a 100 mg/ml, which involved determination of time of paralysis and time of death of the worms.