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Yo Kato
An increase in the incidence of esophageal adenocarcinoma and gastric cardia cancer has been reported in Western countries. However, the lack of universally accepted criteria for the esophago-gastric junction (EGJ) continues to result clinically in confusion in diagnosis of gastric cardia cancer, esophageal adenocarcinoma and Barrett’s esophagus (BE), not only in Japan but also in Western countries. The definition of real EGJ would minimize bias and error and lead to etiologic hypothesis.