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Nasser Almousa, Osama Alshaya
Chondromyxoid Fibroma (CMF) is a rare benign aggressive cartilaginous tumor that represents less than 0.5% of all bone tumors. It most commonly arises from the metaphysis of long bones. However, CMF can rarely arise from other short bones as well as the hand and foot bones. Moreover, it is characterized by some radiological findings, most described as a well circumscribed lytic lesion with scalloped and sclerotic margins. Histopathology is required to confirm the diagnosis of CMF since this tumor is known for its unique histopathological characteristic findings as well. The mainstay treatment is surgical excision via curettage with or without bone grafting or cementing. In this article, we report the diagnosis and management of an 18-year-old male with a painful CMF arising from the 5th metatarsal bone of the right foot that has recurred after curettage and bone grafting surgery, ultimately managed with marginal excision of the tumor and resection of half of the 5th metatarsal bone followed by reconstruction.