临床药理学与生物药剂学

抽象的

Effect of Oral Supplement “Lycopene” On Reducing the Signs of Skin Ageing

Elizabeth Tarshish, Karin Hermoni and Stephen R Schwartz

In today’s world physical appearance is important not only as a symbol of identity, but also as an indicator of health and youth and there is a growing awareness that beauty starts from within. This study was designed to evaluate the effect of a tomato based oral supplement formulation (Lycoderm) containing different phytonutrients including lycopene the red tomato carotenoid on skin appearance after 16 weeks of use. A panel of 60 subjects was divided in two groups of 28 and 32 subjects provided with the placebo and Lycoderm capsules, respectively. Skin carotenoid level, image analysis of photography, questionnaire for assessment of skin condition and expert visual grading of facial wrinkles were obtained before treatment and every month for the course of the study. Results indicated a statistically significant increase in skin carotenoid levels in subjects who ingested Lycoderm, but no remarkable change in the placebo group. There was also a significant reduction in the appearance of lines and wrinkles in subjects using Lycoderm. The subjects noticed multiple skin benefits such as skin brightness and tonality, skin hydration and overall skin condition after using Lycoderm. Based on the confines and conditions of this study oral supplementation with Lycoderm resulted in significant increase in skin carotenoid level as well as tangible benefits to skin.