疼痛与缓解杂志

抽象的

Effect of Oxycodone in Post-operative Pain Management

Ghassan Kloub*

Aims: To study the efficacy of oxycodone for short-term pain management in post-operative patients in a realworld setting.
Methods: A 15-item survey was given to 263 post-operative patients undergoing ENT, general, local sedation, obstetrics/gynecology, ophthalmic, orthopedic, plastic and urological surgery at the department of anesthesiology, Al Garhoud Private Hospital, Dubai, UAE. Each patient answered all 15 questions. Bivariate analysis was used to determine the correlation between pain score and age, gender, and operation type. Multivariate analysis was used to assess the effect of age, gender and type of operation on pain scoring. Distribution of oxycodone adverse effects was also determined.
Results: All 263 patients (males 91 [34.6%]; female 172 [65.4%]) completed the survey. About half (139 [52.9%]) the population belonged to Gulf countries. Surgical procedures included ENT (13), general (65), local sedation (21), obstetrics/gynecology (24), ophthalmic (38), orthopedic (29), plastic (69) urological (4). A total of 220 (83.7%) patients had no pain and 20 (7.6%) patients reported a pain score of ≥5. Statistical analysis showed no effect of correlation with gender and weak negative correlation with age. Obstetrics/gynecology and orthopedic surgeries were positively associated with a higher pain score. All patients (263 [100%]) were pain free with no adverse effects.
Conclusions: Oxycodone was effective in relieving short-term pain after most surgeries and was found to be well tolerated irrespective of type of surgery.