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Diyari Abdulkhaleq Lor
Specific histological alteration in appendices was studies using immuno-histochemical technique against substance P.Fifty patients aged 3-45 years (21 male and 29 female) admitted Azadi Teaching Hospital with clinical sign and symptoms of appendicitis were involved. Significant differences (p≤0.034) was detected at age 11-30 years of ages with clinical suspected appendicitis in most patients while right iliac fossa pain, vomiting and nausea were predominate clinical symptoms yet nonspecific signs of appendicitis.