药代动力学与实验治疗学杂志

抽象的

Formulation of the Tazarotene Cutaneous Gel and Its Physicochemical Characteristic.

Talieh Taheri, Sayed Alireza Mortazavi and Alireza Dabir Siaghi

Treatment of psoriasis is divided to three main types: moderate treatment (moisturizers, phototherapy and etc.), low treatment (changing the life style) and high treatment include systemic medications.

Tazaroten is one of the most effective and the most applicable dermal medicine in treatment of two mentioned diseases that available in form of gel, cream and foam. This agent is one component of vitamin A derivatives and it is a selective receptor of acetylene retinoid that binds to beta and gamma retinoid acid receptors.

The purpose of this study is formulation of cutaneous gel of Tazarotene 0.1% that is not available in the internal market of medication in Iran.