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Debpratim Chakraborty and Nisha Lama Yolmo
From Dec 2019 the disease Covid-19 stated being epidemic in China and Outbreak throughout the world. WHO announced it pandemic on 11th Feb 2020.The most common symptoms of COVID-19 patients are fever, dry cough and tiredness.
There are mainly two broad categories of test for the diagnosis of Covid-19s, e.g. the RT-PCR test and Antibodies detection test. There is no specific treatment but the symptomatic treatment must be categorized like symptomatic treatment, oxygen therapy, treatment of co-infections, prevention of complications and septic shock.
The viral replication takes place after binding with the ACE2receptor, injecting the genome into the host cell, Translation and replication multiply the RNA based nuclear material. After that packaging is takes places and ultimately viral multiplication successfully completed in the presence of various enzymes. The replication can inhibit by blocking the receptor binding or by enzyme inhibition.
Several Clinical Trials and Researches are going on though out the world. A Chinese research team has found a compound called “11a” is less toxic and more effective. Another research said that Interferon-beta-1-b may be a key component for the treatment of COVID-19. Remdesivir, an Ebola drug shows 31% faster recovery than a placebo. Chinese based vaccine’s first human clinical trial was successful and Research on vaccine of Oxford University’s human clinical trial is going “very Well”.
In such a short time, we have advanced our knowledge and research about the virus and the disease a lot so in future we will must overcome and get a peaceful life.