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Genotoxicity of Nanoparticles

Oleksandr H Minchenko, Olha v rudnytska, Dariia O Tsymbal, Olha V Rudnytska, Dmytro O Minchenko

Various nanoparticles have distinctive and remarkable material properties, different from bulk materials with all the same chemical composition, and potential technology applications, including those in biology and medicine. Many of them have recently emerged as a new option for cancer treatment, bioengineering, and gene therapy, but inconsistent data on cytotoxicity and limited control over all such nanoparticles behavior currently in restrict predictability of such applications. We have studied genotoxicity of different nanoparticles: single-walled carbon nanotubes (SWCNT), C60 fullerene, cerium dioxide, chromium disilicide, and titanium nitrite nanoparticles [1 - 7].