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HRP2 and HRP3 and the Performance of Diagnostic Tests for Malaria

María Luz Gunturiz Albarracín

As mentioned in the recently published article, currently, there is little evidence to document the true extent of HRP mutations worldwide. In countries where malaria is endemic, it is necessary to evaluate the genetic variability of the HRP2 and HRP3 genes in order to determine which mutations are present in each country with a view to improving the diagnosis and interpretation of the results obtained by Rapid Tests (RDT) and molecular factors, which could reduce the occurrence of false negatives and, in the medium and long term, improve malaria management programs and interventions [1].