乳腺癌：当前研究

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Immediate Breast Reconstructions after Mastectomy due to Breast Cancers with the use of Serasynth and Seragyn BR Synthetic Meshes. Single-Oncological Center Experience, Analysis of Complications

Aleksander Grous, Slawomir Mazur, Pawel Winter, Krzysztof Kozak, Agnieszka Jagiello Gruszfeld, Marcin Napierala, Zbigniew Nowecki

Purpose: Mastectomies with immediate reconstruction are the standard of treatment method in patients with breast cancer who cannot be treated with conserving breast surgery. The use of meshes in reconstructive breast surgery has become a gold standard. The purpose of the study was to analyze the complications and own experience after mastectomies with immediate breast reconstruction with the use of Serasynth and Seragyn BR synthetic meshes.

Methods: In the period from December 2017 to July 2020, 118 reconstructive surgeries of the breast were performed in the department of breast cancer and reconstructive surgery in Maria Sklodowska-Curie memorial cancer center and institute of oncology in Warsaw, Poland with the use of Seragyn BR and Serasynth meshes in 93 patients operated for breast cancer. 78 Serasynth meshes (Group I) and 40 Seragyn BR meshes (Group II) were implanted.

Results: The most common complication was persistent seroma collection, which was reported in 17.9% of cases in group I and 25% in group II. Skin inflammation was reported in 7.6% and 17.5%, while infections in 2.5% and 5% of the surgically treated breasts of Group I and Group II patients. Reoperation was required in 5.1% and 5% of the patients in group I and group II. The percentage of complications was lower when Serasynth rather than Seragyn BR meshes were implanted. The frequent incidence of the seroma collection did not contribute in any significant way to serious complications such as the need of removal of mesh/implant or infection. The complications, which developed following the implantation of both mesh types, were similar to those presented in other publications concerning mastectomy with a simultaneous breast reconstruction with synthetic meshes. The percentage of implant losses/explanations in the discussed group of patients was lower than that reported in literature.

Conclusion: Despite of the complications, both types of meshes can be considered as safe additions to reconstructive breast surgeries.