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Ramachandramohan M and Mamatha P
This study provides a comprehensive description of skin histopathology of fresh water fish, Glossogobius giuris, after exposing them to 96 hrs (0.25 ppm, 0.5 ppm and 1.0 ppm) of Neem oil and its effects were determined. Mature fish weighing 12 ± 2 g were selected. Experiments were performed and all changes in the specimens were determined at each concentration. The results indicated that the intracellular spaces, the separation of individual cells by muscular dystrophy, necrotic change, vacuolization and degeneration of cells, hyperplasia and hypertrophy of epidermis, results of present study revealed that the acute neem oil toxicity affects mildly and cause less effects on the structure of skin and it may not as impact as organophosporus pesticide on Gobiid fish population in the habitat i.e. Cauvery delta region of Karnataka, India.