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Incidence and Risk Factors of Acute Kidney Injury after Esophageal Cancer Surgery: A Nested Case-Control Study

Washi Wang

Acute Kidney Injury (AKI) is a critical postoperative complication following esophageal cancer surgery, often leading to adverse patient outcomes. This nested case-control study aimed to investigate the incidence and identify risk factors associated with AKI in a cohort of 500 patients undergoing esophageal cancer surgery. The study found an incidence of 13.6% for AKI within the first seven days post-surgery. Key risk factors included age (>65), pre-existing Chronic Kidney Disease (CKD), extensive surgical procedures, intraoperative hypotension, blood transfusions, and postoperative complications. These findings emphasize the importance of tailored preoperative assessments, vigilant intraoperative management, and postoperative care to mitigate the risk of AKI in esophageal cancer surgery patients.