临床药理学与生物药剂学

抽象的

Innovative Approach to Diagnosis, Risk Factor, and Management of Gestational Diabetes Mellitus (Gdm)?Mother and Offspring

Krishna Babu Ojha, Anurag, Soumyadip Mukherjee, Ravi Rajput, Rupali Vinod Yadav

Background: One of the main barriers for obtaining improved maternal and child health is Gestational Diabetes Mellitus. it affects around 5% of pregnancies that increases the risk of caesarean and surgical vaginal birth, macrosomia, shoulder dystocia, neonatal hypoglycaemia, and hyperbilirubinemia for both the mother and the unborn child. In this review article we focused on the various parameters that affects Gestational diabetes mellitus like, pathophysiology, epidemiology, risk factors and treatment.

Body: An extensive literature review was done from the standard databases such as Scopus, Elsevier, and PubMed using standard keywords “Gestational Diabetes”, “Diabetes”, “Pregnancy disorder”. Here, we explore the effects of Gestational Diabetes Mellitus on long- term maternal and newborn outcomes as well as health concerns that will probably last into the next generation. We discuss current clinical survey data and model of Gestational Diabetes Mellitus to better understand the underlying pathophysiology of the disease and the timely need to expand our scientific toolbox in order to identify strategies to prevent and treat Gestational Diabetes Mellitus.

Conclusion: While discussing about the gestational diabetes mellitus with the advance clinical care, in addition to the challenges currently faced in the Epidemiology, and techniques of diagnosis, Pathophysiology, risk factor, management of Gestational Diabetes Mellitus.