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Coppola M and Mondola R
Between 1997 and 2011, more than 200 new substances have been officially notified in European Union via the Early Warning System with the largest number of compounds ever reported in a single year in 2011 (49 substances). In 2010, an internet snapshot anticipated the presence of 5-iodo 2-aminoindan (5-IAI) within the recreational drug market. In 2011, this compound, a psychoactive analog of p-iodoamphetamine, was identified in United Kingdom. The aim of this paper is to summarize the clinical, pharmacological and toxicological information currently available about this new potential recreational drug.