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Leiomyosarcoma of the Breast: A Case Report

Mazyar Kavousi, Stacy Ries DO, Dominic Semaan MD, Riffat Ahmed

Leiomyosarcoma is a rare type of malignancy that begins in smooth muscle tissue and primarily presents in patients between the age of 24 and 86-years old. Leiomyosarcoma of the breast is a significantly unreported manifestation of stromal sarcomas, with fewer than twenty cases being reported globally. We present a case of a 45-year-old female with hepatic, left renal and multiple bone metastases that presented with a suspicious mass in the left breast following a routine mammogram. The combination of angular and speculated tumor margins warranted additional investigation in the form of an ultrasound and subsequent biopsy. When a patient has a history of leiomyosarcoma and metastatic lesions, further investigation should always be considered if suspicious findings are noted in routine examinations.