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Saddam Hussain*, Taj Muhammad, Atiqur Rahman, Muhammad Akbar, Sajid Ullah1 and Takashiro Akitsu
Diabetes mellitus is a worldwide disease and it grows all over the world in all developing countries. Pakistan is also a developing country and is the 36th largest country in the world. Diabetes mellitus has been spread all over in Pakistan; peoples from both (urban and rural) areas are affected from this disease. Different surveys were conducted at international level as well as in Pakistan to check the prevalence of diabetes mellitus. The aim of this study was to evaluate the time trend of diabetes and diabetes prevalence in Pakistan using a systematic review and meta analysis. A systematic literature search of EMBASE, pubmed, medline and the cochrane library was conducted between January 2000 and August 2020. prevalence estimates of diabetes using a random effects model. The existence of publication bias was tested by Egar regression. This systematic review was reported following PRISMA guidelines. Traditional medicines do not only treat the disease but also fulfill the requirement of nutrition and also have other benefits. Pakistan has 6000 species of plant among which 600-700 plant species are used medicinally. Northern areas of Pakistan have 3000 species of plants among which 124 species are medicinally very important. These surveys were made on both male and female from both rural and urban areas of Pakistan from all four provinces. From all these surveys the current prevalence of diabetes type 2 in Pakistan is 11.77%. In which 11.20% exist in males and 9.19% exist in females. The mean prevalence in all four provinces is: The prevalence of type 2 diabetes in urban areas is about 14.81% and in rural area is about 10.34%. These prevalence in both males and females under the age of 25-45 years. According to international diabetes federation, 26.7% of adults in Pakistan are affected by it in 2022. The total number of diabetes cases is about 33,000,000.