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Non-hodgkin lymphoma (NHL), Epstein bar virus, progesterone receptor, and cross-talking: Micro-environmental approaching of NHL as a new medical hypothesis.

Ahed J Alkhatib

This study explores non-Hodgkin Lymphoma from different perspectives. The present abstract introduces brief lymphomas, Epstein Bar Viruses (EBV), progesterone receptor, and the phenomenon of cross-talk. Lymphomas start from harmful changesin lymphocytes, for the most part Bcells. Immune system cells and NK cell inferred-lymphomas are less normal. The principal lymphoma type that was perceived is Hodgkin lymphoma (HL). The various lymphoma types have allbeen in all called non-Hodgkin lymphomas (NHL) and include different subtypes (like diffuse largeBcell lymphoma, follicular lymphoma and small lymphocytic lymphoma) just as different Tcell lymphomas (Swerdlow, 2008). According to Leak (2011), NHL ranks sixth most common cancer in the United States (US).From an epidemiologic point of view, NHL was mostly prevalent in some areas such as North America, Australia and Europe. On the other hand, the lowest rates were recorded in Asia and Pacific. It has been reported that 1 out of 110 men and 1 of 161 women are affected by NHL during their life span. However, increasing incidence of NHL may due to several factors such as lifestyle, demographic variables including age and gender, occupational conditions and environmental factors, infectious agents, genetics and family history, and autoimmune diseases (Farmanfarma et al., 2020).