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Novel Therapy for Unresectable Hilar Cholangiocarcinoma ‘Klatskin Tumor’ Utilizing Percutaneous Irreversible Electroporation: A Case Report

Mazal N and West D

Unresectable hilar cholangiocarcinoma ‘Klatskin Tumor’ is a rare malignancy with limited treatment options and an overall poor prognosis. Percutaneous Irreversible Electroporation (IRE) is a relatively new ablative procedure with potential for treating unresectable cholangiocarcinoma, improving morbidity, and ultimately prolonging survival. The main benefit of IRE relies in the non-thermal technology which can be considered in patients with hilar tumors given the criticality of the adjacent vessels and bile ducts. This case report describes a 71 year old female with unresectable Bismuth-Corlette Stage IV cholangiocarcinoma who underwent IRE with disease control 13 months after treatment.