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Deyhimi Parviz and Khalesi Saeideh
Rhabdomyosarcoma (RMS) is a malignant soft tissue neoplasm of skeletal muscle origin. The most common sites of occurrence are the head and neck, genitourinary tract, and extremities. Although Rhabdomyosarcoma has a relative predominance for head and neck region, it is less frequent in oral cavity, and accounts for only 0.04% of all head and neck malignancies. Some studies have been showed that soft palate and tongue are the most common sites for oral RMS. We present a case of oral Rhabdomyosarcoma in a 15 year old girl, and demonstrate the clinical, radiological, histological, and immunohistochemical features of this neoplasm.