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Patients with pediatric prostheses suffer from mismatch and early calcification, which causes a high number of re operations

Miguel Angel Maluf

Background: Patients with pediatric prostheses suffer from mismatch and early calcification, which causes a high number of reoperations. Methods: Expandable Polyurethane Stent Valve – EPSV, is composed by flexible polyurethane (PU) cusps is grown on the top of an expandable cobalt-chrome alloy stent, including the formation of three leaflets. Physical, Hydrodynamic, Animal studies, were performed following: ISO 5840-3, 2015. Results: Physical tests. Result of study of surface scanning of pre and post crimp stent, showed no structural modification of the PU. Hydrodynamic test showed a pressure gradient oscillation between 5 to 20mm, in basal or stress conditions respectively. Experimental studies, Sheep were subjected to 3D echo-Doppler study, in 6th follow-up months, which showed satisfactory hemodynamic performance, with low transvalvular gradient (M = 6.60 mm Hg).