临床与实验神经免疫学杂志

抽象的

Pattern of Brain Neoplasm in Khyber Pakhtunkhwa and Afghani Refugees. Hospital Based Descriptive Retrospective Study

Haidar Ali

The term “brain tumor” refers to a set of neoplasms, every single with its own biology, prognosis and treatment; these tumors are well recognized as “intracranial neoplasms”; since some of them didn’t arise from brain tissue (e.g., meningioma’s and lymphomas). Childhood neoplasms are the second most common cause of death after trauma. This study aimed to determine the Frequency and pattern of brain neoplasm in Khyber Pakhtunkhwa and Afghani refugees through hospital based data from 2012 to 2016. This was Hospital based Descriptive Retrospective study. Study setting was (Institute of Radiation & Nuclear Medicine (IRNUM) Peshawar Pakistan. Data were collected from 2012-2016. Cases of primary brain tumor, of both genders and all age groups were included in the study. And cancers other than brain tumor and those having inflammatory lesion of the brain. Cases with incomplete data were excluded. Data was analyzed by using statistical package (SPSS version 23.0. A total of 765 Cases enrolled in study having complete data and were analyzed over a period of five years. Of those 765 cases 197 were Female patients 357 were males and 212 pediatric patients. Male to Female ratio is 4:2. Study mean age for adults was 38.07 ± 15.02 and for pediatrics mean age was 8.72 ± 3.36. Majority of neoplasms in adult was GBM followed by astrocytoma and subtypes of gliomas while in pediatric most of the cases were medulloblastoma followed by gliomas. There was correlation b/w age and disease stage as (p<0.01). This study revealed the distribution of brain tumors in patients attending our institution. The results obtained were comparable with available worldwide data. Majority of the cases were in stage 2 followed by stage 4 and stage 3.