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Solanki S and Dave K*
Osteosarcoma arising from skull base are very rare. We report the case of a 14-year-old female patient who presented with a swelling in the right postauricular region for 6 months, which proved to be a high-grade osteosarcoma. On Chest screening, we found two lung nodules which most likely represent metastases. We describe pre-and post-operative findings on Computed Tomography (CT) and Magnetic Resonance Imaging (MRI). We review the literature of reported cases of primary osteogenic sarcomas of the skull to discuss the common clinical presentation, evaluation methods, and recommended treatment plans.