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Takeo Takahashi, Keiichiro Nishimura and Takafumi YAmano
Radiotherapy plays an important role in the treatment of locally advanced esophageal cancer. And, definitive chemoradiotherapy is widely accepted treatment methods for advanced esophageal cancer. Radiation dose-escalation has failed to improve local control or survivals. However, irradiation techniques have been advancing markedly. 3-dimensional radiotherapy, intensity modulated radiotherapy (IMRT), and particle beam therapy is a highly precise radiotherapy in which the dose distribution can be fitted according to the shape of tumor. Future Directions will evaluate the dose-escalation using highly precise radiotherapy and adequate radiation field for locally advanced radiotherapy.