放射学组学杂志

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Secondary Syphilis with Bone Involvement of the Skull: A Case Report

Herrera-Herrera I*, Escalona-Huerta C, Valle-Zapico JD, Montoya-Bordón J, Ordoñez-González C and Sobrino-Guijarro B

A 40-year-old Human Immunodeficiency Virus (HIV) positive male consulted for headaches and a palpable lump on the scalp with laboratory findings relevant for increased acute phase reactants. Head CT and MR were performed, which showed temporal muscle and adjacent subcutaneous fat swelling, with underlying bone marrow edema and dural enhancement. A positive RPR test and further response to treatment for syphilis clinically confirmed secondary syphilis infection with bone and soft tissue involvement. Osseous involvement in secondary syphilis is relatively uncommon. It may be the first symptom of early-acquired syphilis and should be considered among the differential diagnoses for inflammatory lesions of the skull with overlying soft tissue swelling, especially in HIV positive patients.