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Sero-Epidemiology of Toxoplasmosis among the People of Khorram Abad, Iran

Almasian R, Almasian M and Zibaei M

Toxoplasma gondii is an opportunistic, zoonotic pathogen with a worldwide distribution. There are large variations in the seroprevalence of Toxoplasma infection in different regions of the world. Although toxoplasmosis became a notifiable sectional study aimed to survey the seroprevalence of Toxoplasma infection and its risk factors among people in Khorram Abad. In the present study, simple random sampling was carried out on the referents to 6 medical diagnostic laboratories (from among the 9 laboratories available in the city). The tests were performed on the 1000 blood serum samples using the IFA (immunofluorescent antibody assay) method and the effects of three variables including place of residence, occupation, and marital status were considered. Of the 1000 Khorram Abad studied, 831 (83.1%) were positive for Anti-T. gondii IgG antibody and 169 (16.9%) were negative. Seroprevalence of Toxoplasma infection did vary with residency, material status, and occupation (P<0.05). Our results demonstrate serological evidence of Toxoplasma exposure among Khorram Abad which may be impacting their health. Results of this first study of Toxoplasma infection in Khorram Abad may be useful for the design of optimal preventive measures against infection with Toxoplasma.