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Squamous Cell Carcinoma in Mature Cystic Teratoma Ovary: A Rare Presentation

Aruna Gupta, Garima Shah

Introduction: Mature cystic teratoma also known as dermoid cyst is the most common ovarian tumors accounting for 30%-45% cases.

1. The incidence of Squamous cell carcinoma arising in the mature cystic teratoma is 2%.

2. In this case report we are presenting two cases of squamous cell carcinoma arising in mature cystic teratoma.

Case presentation: Two women of age 62 and 47 years are presented to the gynecology OPD with the complaints of distension and pain in the lower abdomen. On CECT-Features suggestive of mature cystic teratoma was given as the diagnosis. TAH with BSO was done. On histopathologic examination, diagnosis of squamous cell carcinoma arising in the background of mature cystic teratoma was given.

Discussion: Mature cystic teratoma is a common ovarian tumor in young women while squamous cell carcinoma in the setting of mature cystic teratoma is extremely rare. Carcinoma arising in the mature teratoma is common among postmenopausal women. It has poor prognosis but preoperative diagnosis of this malignant transformation of mature cystic teratoma is difficult.

Conclusion: Although mature cystic teratoma is common but its malignant transformation is extremely rare. It carries poor prognosis and has to be diagnosed early. Its preoperative diagnosis is difficult and can be confirmed on histopathology only. The clinicians, pathologists and radiologist should be well aware of this entity and should take it into consideration.