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Hossein Ghazizadeh
Over 60 years have long gone because the first pacemaker becomes inserted. Since then, significant strides in pacemaker technology have boosted the devices' safety and efficacy in treating bradyarrhythmias. Evidence that the electrical function of the mammalian heart is required for a regular mechanical role is provided by the recurrent stimulation of cells in specialized "pacemaker" regions. The electrical activity of the myocardium and the heart's normal cooperative electrical function are related to the formation of action potentials in individual cardiac cells. The batteries and electronics are housed in a container called a pulse initiator, and lines that attach to the myocardium are used to provide a depolarizing pulse and detect intrinsic cardiac stimulation.