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Sean P. J. Lynch
Chronic fatigue syndrome is a case definition for conditions of chronic, disabling physical and mental fatigue which are not fully explained by medical or psychiatric causes (NICE, 2007). There has been much controversy over both the case definition and its management (Lynch, 1994). Some expert and patient groups have favoured other case definitions such as ME, CFIDS and believe that these may represent distinct groups with different aetiology. All of these case definitions are imperfect and may have limitations.