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The Role of Platelets in Viral Hemorrhagic Fevers
Dermot Cox, Maria Salvato and Juan Carlos Zapata
Arenaviridae, Bunyaviridae, Filoviridae and Flaviviridae are all RNA viruses that can induce a coagulopathy in infected patients. While there is a paucity of information on the cause of this coagulopathy, these viruses all produce a severe thrombocytopenia. Here, we review the literature on viral hemorrhagic fever and discuss the role played by platelets in the coagulopathy. We also discuss the possibility of using anti-platelet agents to moderate the coagulopathy, a strategy that might have a role to play in treating patients infected by these viruses.
免责声明: 此摘要通过人工智能工具翻译，尚未经过审核或验证。