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Treatment of Arsenic Toxicity during APML Treatment in a Pediatric Patient
Ripal Patel, Omayma Kishk, Dimitrios A Savva, Adrian Holloway
A 17-year-old healthy female was presented with altered mentation after a fall. The workup revealed a new onset of APML. Chemotherapy was initiated. She developed MODS requiring ECMO and CVVHDF. Two days after discontinuation of support, the patient developed acute worsening mentation, emesis, diarrhea, tachycardia, fever, creatinine of 9.58 mg/dL, and prolonged QTc-582, indicating arsenic poisoning from chemotherapy.
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