世界药理学与毒理学杂志

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Unleashing the Power of Pharmacogenetics: A New Era in PersonalizedMedicine

Laura Sartiani

Pharmacogenetics, the integration of genetics and pharmacology, is a rapidly advancing field with the potential to revolutionize healthcare and usher in a new era of personalized medicine. By studying how an individual’s genetic makeup influences their response to drugs, pharmacogenetics aims to optimize medication choices and dosages, maximizing efficacy while minimizing adverse reactions. This article provides an overview of pharmacogenetics, exploring its principles and mechanisms, as well as its practical applications in individualized drug selection, predicting adverse drug reactions, and dose optimization. Furthermore, it discusses the future implications of pharmacogenetics, including its integration with electronic health records, the development of novel therapies, and its potential impact on population health. Embracing pharmacogenetics has the power to transform clinical practice, leading to safer and more effective treatments tailored to each patient’s unique genetic profile.