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Why is Obesity a risk Factor for Atherosclerosis
Ruth Prabhu
Obesity is a multifactorial chronic disease characterized by an accumulation of visceral and subcutaneous fat, which leads to a predisposition toward cardiometabolic diseases. A plethora of mechanisms, including abnormalities in lipid metabolism, insulin resistance, inflammation, endothelial dysfunction, and inflammasome activation have been suggested to underlie the relationship between obesity and atherosclerosis.
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