肿瘤学研究与治疗杂志

抽象的

Xeroderma Pigmantosum with Multiple Malignant Lesions, Present in Siblings Linking it to Genetic Aspect of the Disease and Possible Treatments

Dipen Mistry*, Dwija Patel*, Maitrik Mehta*, U Suryanarayana* and Anshum Patel*

Being a Geno dermatosis, photosensitive disorder Xeroderma Pigmantosum (XP) is a rare autosomal recessive disorder. Patient with XP commonly presented with an interactable and dermatological disease. Patients with XP are prone to cutaneous, mucosal malignancies and ophthalmic complications. Reason being inability to repair the Ultra Violet (UV) radiation dispensed damage to Deoxyribonucleic Acid (DNA), genetic nature of disease is revealed. Not only genetic but environmental factor plays big role in course of disease. In XP cutaneous and mucosal Basal Cell Carcinoma (BCC) and Squamous Cell Carcinoma (SCC) or melanoma is most common.