国际药学与生命科学研究与发展杂志

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A Review on 3D Oral Printed Tablets: A Breakthrough Tool for Individualized Therapy According To Each Patient's Individual Circumstances with Different Techniques and Polymers Used For Formulation

Pujan V. Padsala, Harmish A Asodariya, Yash S Shah, Dip Ranpariya, Dr. Hiral Panchal

When treating patients from various origins with distinct cultures, metabolisms, and needs, interindividual variability is becoming a more widespread concern. Because dose modification typically relies on empirical techniques, there is a strong probability that undesirable side effects may manifest.The pharmaceutical industry is being revolutionized by three-dimensional (3D) printed pharmaceuticals as prospective instruments to create individualized therapies tailored to each patient's unique needs,taking into consideration their age, weight,pharmacogenetic,comorbidities, pharmacogenetic,and pharmacokinetic features. Only three of the various processes used in additive manufacturing, or 3D printing, are primarily employed in the 3D printing of pharmaceuticals: printing-based inkjet systems, nozzle-based deposition systems, and laser-based writing systems. Each method has a number of downsides, and the kinds of polymers thatare easily accessible don't necessarily have the best qualities for each medicine. The purpose of this study is to provide an overview of the current methods used in 3D printing medications, highlighting their advantages and shortcomings as well as the necessary polymers and medications for a successful print. Also covered will be the main applications
of these approaches.