国际药学与生命科学研究与发展杂志

抽象的

DESIGN AND DEVELOPMENT OF TRANSDERMAL DRUG DELIVERY SYSTEM

S. K. Gupta, Ravikant Gupta, Sanjay Kumar Yadav, Mousumi Kar, D.K. Jain

In the course of development of microspheres preparation techniques, the encapsulation of hydrophilic drugs with high entrapment efficiency has been a problem, as the commonly used technique like single emulsification technique and w/o/w double emulsification technique show low entrapment of the hydrophilic drugs. The problem is overcome by using by using w/o/o double emulsification technique, several modifications have been done in this technique one of most widely and effective technique in w/o/o double emulsification is the solvent diffusion technique. In this brief review comparison of w/o/o double emulsification technique with other methods and details about the w/o/o double emulsification technique and the drugs encapsulated using this technique will be discussed.