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Sandra Correa*
The BSCL2 gene encodes seipin, a nonenzymatic protein. It is involved in the disorders lipodystrophy and seipinopathy. All seipin functions, which were named in 2001, are still poorly understood. As a result, we analysed a large amount of research in search of a pattern that could explain widely reported aspects of seipin expression disorders. Similarly, this review demonstrates how this protein appears to have tissue-specific activities. We end by offering a theoretical model to explain how seipin might be involved in the triacylglycerol production process.