国际药学与生命科学研究与发展杂志

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MEDICATION CONCORDANCE AMONG THE OUT-PATIENTS WITH TYPE 2 DIABETES IN KANPUR AT NORTHERN INDIA

Sudhir Singh Gangwar, Parimalakrishnan. S, Akram Ahmad, Seo Pratap Singh

Medication nonadherence is a pervasive medical problem that is common among patients with chronic disease generally and type 2 diabetes in particular. There are two types of nonadherence (i) unintentional nonadherence and (ii) intentional nonadherence. To evaluate medication adherence in type 2 diabetes patients, determine the outcome of the therapeutic management in the level of blood glucose. The present study is a prospective cross sectional pilot study, it was conducted for 12 weeks, between January and March 2012, by using research questionnaire, Morisky 8-Item Self-Report. 103 patients are selected randomly and interviewed. Of the selected patients, 20.39% patients were completely lost the follow-up, 5.82% patients were not regularly visiting and 3.88% was declined to give consent. Rest of the 72 patients are the subjected for the further studies. 72 subjects, 62.5% were male and 37.5% were female. 94.44% were married and 75% of the subject was completed their graduation while 15.28% was completed secondary school whereas 9.72% do not have any formal education. The occupation of the subjects represented that 47.22% were employed, 40.28% were self-employed and 12.5% were unemployed. 91.67% of subjects HBA1C level was in abnormal category. The total cholesterol level was also measured, 58.33% subjects were having abnormal level (< 200mg/dl). Medication nonadherence of ambulatory type 2 diabetes patients is seen significant. Missing of dose, forgetfulness and expenditure on medicines were the highly observed factor for the medication compliance. Nevertheless, low level of adherence shown to have considerably affected on patients’ blood glucose level since large number subjects had blood glucose level was in abnormal level. Pharmacists can help to upsurge the medication adherence and self-management practices of these subjects in the study site to achieve maximum benefits of prescribed treatment regimen.