生物化学与生理学：开放获取

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Serum Calcium and Risk of Cardio Vascular Diseases with Menopause in North Indian Women

Neha Sharma and Girdhar Gopal Kaushik

Menopause is a natural transition but has inconvenient effects on ageing women due to lack of health/ treatment awareness. Calcium supplements, which are commonly recommended to elderly people, particularly post menopausal women. Recent evidence warns that taking calcium supplements might increase myocardial infarction (MI) risk. We aimed to evaluate the relation of different biochemical and anthropometric parameters with baseline characteristic of postmenopausal women, related to risk of cardio vascular diseases (CVD). Correlation between fasting serum lipid profile [serum total cholesterol, serum triglyceride, serum HDL, (AIP; logTG/HDL)] with serum calcium and different anthropometric parameters in 200 menopausal women aged 45-56 years was studied retrospectively. All biochemical parameters were measured on fully automated analyser using standard reagent kits. History was taken through questionnaires from subjects with complains regarding menopause after taking verbal consent. In menopausal women between age 45-48 years when serum total cholesterol and serum triglyceride were in higher range and statically significant, at the same atherogenic index of plasma (AIP) was not significant, while above 48 years in age when serum calcium found to be in the normal range (8.7-11.0 mg/dl), atherogenic index of plasma (AIP) and serum lipid parameters show a statically significant relation to risk of CVD, and most of our subjects were unaware about menopausal symptoms and it’s treatment because of illiteracy. The counseling activity should go on complained regarding menopause with all anthropometric and biochemical parameters.