国际药学与生命科学研究与发展杂志

抽象的

THE EFFECT OF TITANIUM DIOXIDE NANOPARTICLES ON SALIVARY ALKALINE PHOSPHATASE ACTIVITY

Eaman AS AL-Rubaee, Suha T Abd, Nadia M Kadim

The structural and optical properties of the titanium dioxide nanoparticles (TiO2NPs) have been investigated using (UV-Vis) spectrophotometer and SEM. The produced nanoparticles show small and about sharp round peaks around 220nm. The produced nanoparticles have a spherical shape with an average particle size �?�?50 nm. The effect of titanium dioxide NPs was studied on the activity of Alkaline Phosphatase (ALP) in the saliva of 25 patients with gingivitis in comparison to 20 healthy subjects with the average age about 22-23 years for both groups. The results correlated with the observation that salivary alkaline phosphatase activity increase in patient with gingivitis in comparison to control group and salivary ALP activity inhibited by titanium dioxide nanoparticles.