营养科学研究杂志

抽象的

The European Prospective Investigation into Cancer and Nutrition (Epic) Cohort Study on Meat, Eggs, and Dairy Products and Breast Cancer Risk

Vitoro Krough

Background: The Western diet is linked to an increased risk of breast cancer.

Objective: We explored the connection of meat, egg, and dairy item utilization with bosom malignant growth risk by utilizing information from the European Forthcoming Examination concerning Disease and Sustenance (EPIC).

Design: Data on diet were gathered from 319,826 women between 1992 and 2003. Multivariate Cox proportional hazard models were used to calculate disease hazard ratios.

Results: Breast cancer cases (n = 7119) were tracked for an average of 8.8 years. When categorical and continuous exposure variable models were examined, neither the consumption of any of the food groups under investigation nor the risk of breast cancer were found to have a consistent association. In the categorical model, eating a lot of processed meat was linked to a small increase in the risk of breast cancer (hazard ratio: 1.10; 95% CI: 1.00, 1.20; Compared to the lowest quintile, the highest: P for the trend is 0.71). A link between butter consumption and premenopausal women was found in subgroup analyses (hazard ratio: 1.28; 95% CI: 1.06, 1.53; Compared to the lowest quintile, the highest: Trend P value = 0.21). Red meat showed heterogeneity across countries (Q statistic = 18.03; the proportion of meat cooked at high temperatures was significantly (P = 0.023) explained.

Conclusions: We have not in every case recognized admissions of meat, eggs, or dairy items as chance elements for bosom malignant growth. High-temperature cooking may play a role in the relationship between red meat consumption and breast cancer risk, which should be the subject of further research.