English 
Spanish 
Russian 
German 
French 
Japanese 
Portuguese 
Hindi 开放获取期刊获得更多读者和引用
700 种期刊 和 15,000,000 名读者 每份期刊 获得 25,000 多名读者
索引于
- CAS 来源索引 (CASSI)
- 哥白尼索引
- 谷歌学术
- 夏尔巴·罗密欧
- 打开 J 门
- Genamics 期刊搜索
- 学术钥匙
- 期刊目录
- 乌尔里希的期刊目录
- 电子期刊图书馆
- 参考搜索
- 哈姆达大学
- 亚利桑那州EBSCO
- OCLC-世界猫
- 学者指导
- SWB 在线目录
- 虚拟生物学图书馆 (vifabio)
- 普布隆斯
- 欧洲酒吧
- ICMJE
有用的链接
开放获取期刊
分享此页面
抽象的
Uplc-Ms/Ms Method for The Simultaneous Determination of Plasma Catecholamines And Their Metabolites
Mahyar Yousefi
Phaeochromocytomas and paragangliomas (PPGLs) are rare tumors of adrenal chromaffin cells or extra-adrenal paraganglia. they're difficult to diagnose due to the non-specific clinical symptoms like hypertension, palpitations, flushing and sweating. Inappropriate catecholamines (CAs) production was normally used for the diagnosis of PPGLs within the clinical laboratory. Traditionally, 24-hour urine was used for analysis to permit for intermittent secretion of CAs by PPGLs. The guideline recommends screening of fractionated urinary metanephrines (MNs, the metabolites of CAs) or plasma free MNs using high performance liquid chromatography with electrochemical detection (HPLC-ECD) or liquid chromatography